A study that casts some light on why we diet and can’t lose weight…and also points up why one rodent is not like another. IE, if you’re doing a study, species matters.

There’s a second study like this one, which points to a hormonal deficiency at birth, while this one seems to indicate it could occur later in life.

Some of these studies are in Petri dishes, where it doesn’t do very much about that bag of donuts we just consumed…but some are not. At least they’re identifying chemical pathways, which could point in useful directions. The way we can not eat but not lose weight is a very complex question, as it appears, going all the way down into cellular levels, and may have a survival value when it comes to lean times, or when it comes to the need of women to sustain a child. And it’s become a problem to high-stress periods of life when people eat for energy and aren’t getting that either, as this study sort of points out. Just kinda interesting, in solving one of life’s little injustices. Jane and I have been kind of in a holding pattern on the diet, where it comes to dropping any points, but we’ve not fallen victim to the massive re-gain. We’re getting through the fall, when we have my birthday and Jane’s birthday, Thanksgiving, Christmas and New Year’s. Having our nice holiday food, but being mindful that not every day in between is a holiday. Post New Year’s we’re going back on a more restrained diet to finish the Battle of the Bulge. The weight didn’t come on us all in one year. It’s taking more than a year to lose it. But we’ll get there.

Fat and energy: Science Daily